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After absorption, GA is transported to the liver primarily via carrier-mediated mechanisms and undergoes phase II metabolism to form glucuronide and sulfate conjugates (Ploeger et al., 2001)

4) GPX4-independent ferroptosis suppressionDHODHCoQ10H 2 pathway in the mitochondria: Dihydroorotate dehydrogenase (DHODH), a flavin-dependent enzyme localized to the mitochondrial inner membrane, catalyzes the fourth step of pyrimidine biosynthesisconverting dihydroorotate (DHO) to orotate (OA)while transferring electrons to mitochondrial ubiquinone, reducing it to CoQ10H 2 , which acts as a radical-trapping antioxidant (107)

Indications for B12 shots Most people have enough of this nutrient